Nucleosides and Analogues
Sigma Aldrich Fine Chemicals Biosciences Adenosine 15N5 5 triphosph10MG
Adenosine 15N5 5 triphosph10MG
Medchemexpress LLC 6-O-methyl guanosine | 7803-88-5 | MFCD01723912 | 99.7% | 297.27 g·mol⁻1 | C11H15N5O5 | 5 MG
6-O-methyl guanosine is a modified nucleoside for biochemical research, reported to inhibit colony-forming ability in certain xeroderma pigmentosum cell lines. It is supplied as a solid reagent intended for in vitro studies and analytical applications.
- High purity (99.7%) suitable for analytical and biological experiments.
- Molecular weight 297.27 g·mol⁻1; formula C11H15N5O5.
- Soluble in DMSO (130 mg/mL); sparingly soluble in water (2 mg/mL); ultrasonic or warming recommended to aid dissolution.
- Stable as a powder at -20°C for extended storage.
- Available in small research quantities (for example, 5 mg) for laboratory use.
Medchemexpress LLC Uridine | 58-96-8 | MFCD00006526 | 100.0% | 100 MG
Uridine (Standard) is an analytical standard used for research and analytical applications. It functions as a reference standard supplied assay in various experiments, including HPLC, GC, and MS. This compound is an endogenous metabolite and also a disease marker for Nervous System Disorder.
- Used as a reference standard supplied assay
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
- Molecular weight: 244.20
- Formula: C9H12N2O6
- Appearance: white to off-white solid
- Endogenous metabolite and disease marker for Nervous System Disorder
TARGETMOL CHEMICALS INC 5-DEOXYADENOSINE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 5'-Deoxyadenosine (5′-dAdo) is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genetic material which has long been of interest in understanding the mechanism of aging neurodegenerative diseases and carcinogenesis. The normal form of deoxyadenosine used in DNA synthesis and repair is 2'-deoxyadenosine where the hydroxyl group (-OH) is at the 2' position of its ribose sugar moiety. 5'-deoxyadenosine has its hydroxyl group at the 5' position of the ribose sugar. purity: 99%
Medchemexpress LLC a-D-Glucosamine pent 10g | 7784-54-5 | 10 G
Alpha-D-glucosamine pentaacetate is the fully acetylated derivative of D-glucosamine used as an intermediate and reagent in glycobiology and carbohydrate chemistry. It is supplied as a solid for synthetic and analytical workflows, including derivatization and glycan synthesis.
- Fully acetylated amino sugar derivative for carbohydrate synthesis.
- High purity suitable for research (≥97.0%).
- Useful as a synthetic intermediate and for glycobiology studies.
- Solid form for convenient storage and handling.
- Molecular formula C16H23NO10; molecular weight 389.35 g·mol⁻¹; CAS 7784-54-5.
Medchemexpress LLC Malvidin-3-O-arabinoside chloride | 28500-04-1 | 97.1% | 498.86 | 5 MG
Malvidin-3-O-arabinoside chloride (M3A chloride) is a research chemical that ameliorates ethyl carbamate-induced oxidative damage by stimulating AMPK-mediated autophagy. It is used in studies to understand cellular processes related to oxidative stress and autophagy.
- Stimulates phosphorylation of AMP-activated protein kinase (AMPK)
- Upregulates LAMP-1 expression
- Restores lysosomal acidity and strengthens lysosomal functions
- Inhibits excess reactive oxygen species (ROS) generation
- Enhances glutathione (GSH) levels and autophagy flux
- Upregulates LC3-II/LC3-I ratio
Cambridge Isotope Laboratories 5-Fluoro-2-deoxycytidine 5-triphosphate ammonium salt (unlabeled) (in solution) CP 95% 100 umol
5-Fluoro-2-deoxycytidine 5-triphosphate ammonium salt (unlabeled) (in solution) CP 95% 100 umol
Apexbio Technology LLC 6-O-Propynyl-2-deoxyguanosine 25mg
6-O-Propynyl-2-deoxyguanosine (CAS 1640051-47-3) is a modified nucleoside featuring an alkyne functional group at the 6-position of deoxyguanosine This structural modification enables its use in bioorthogonal click chemistry reactions facilitating site-specific labeling and conjugation in nucleic acid research The alkynyl group serves as a chemical handle for copper-catalyzed azide-alkyne cycloaddition allowing researchers to attach probes or other functional molecules 6-O-Propynyl-2-deoxyguanosine is utilized for studying DNA structure dynamics and for the development of modified oligonucleotides in biochemical and molecular biology assays
Medchemexpress LLC 6-Thio-2'-Deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 25 MG
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase. This product is for research use only and not for sale to patients.
- Treatment results in rapid cell death for the vast majority of cancer cell lines tested, with IC50s between 0.7-2.9 μM.
- In A549 lung cancer cell-based mouse xenograft studies, it causes a decrease of the tumor growth rate, superior to that observed with 6-thioguanine treatment.
- It increases telomere dysfunction in tumor cells in vivo.
Medchemexpress LLC Guanosine 5'-diphosphate sodium | 43139-22-6 | 99.9% | 465.18 | 10 MG
Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K+ channels. It functions as an iron mobilizer by forming a complex with hepcidin, inhibiting the hepcidin-ferroportin (FPN) interaction and modulating the IL-6/Stat-3 pathway. This compound can ameliorate Turpentine-induced anemia of inflammation (AI) in mice when combined with FeSO4, making it suitable for research on AI.
- Activates adenosine 5'-triphosphate-sensitive K+ channels.
- Functions as an iron mobilizer.
- Inhibits hepcidin-ferroportin (FPN) interaction.
- Modulates the IL-6/Stat-3 pathway.
- Ameliorates Turpentine-induced anemia of inflammation (AI) in mice.
- Suitable for research on anemia of inflammation.
Apexbio Technology LLC Adenosine 58-61-7 1g
Adenosine (CAS 58-61-7) is a purine nucleoside consisting of adenine covalently linked to a ribose sugar via a -N9-glycosidic bond Endogenously adenosine modulates cellular signaling through activation of specific G protein-coupled adenosine receptors (A1 A2A A2B and A3) influencing diverse physiological processes such as neurotransmission vasodilation and immune responses In biomedical research adenosine is widely utilized to investigate purinergic signaling pathways cardiac function and the regulation of inflammatory and neuroprotective mechanisms as well as serving as a pharmacological tool in receptor binding and functional assays